Track Descriptions

Assay Development and Screening

Advances in novel and physiologically relevant assay technologies remain the main drivers for the success of screening campaigns as they shape and evolve screening strategies and assay repertoire. This track will focus on recent assay innovations across the field including applications of new instrumentation and hardware, will review approaches to and availability of collections for chemical and RNAi screening with emphasis on follow up studies relating to "hit to lead optimization" and "cellular pathway analyses", and conclude with an overall review of the informatics for screening data acquisition, storage and analysis. Topics include:

  • Addressing Difficult Targets
  • Assays in Toxicology, Agriculture and Consumer Products Research
  • Bioassays for Biologics
  • Biosensor Based Cell Based Assays
  • Cellular pathways analyses
  • Engineered Isogenic Cell Lines for Assay Development
  • Expanding the Chemical Space for Screening
  • Hit to Lead Chemical Optimization
  • Label Free Technologies
  • Libraries for Chemical and Functional Genomics Screening
  • Live Cell Based Assays
  • New Instrumentation for Assay Development
  • Novel Assay Development Technologies
  • Novel Assays for IPS Cells
  • Phenotypic Based Assays

High-Throughput Technologies

This track focuses on the innovative tools, technologies, and techniques that enable automated and/or high-throughput activities that improve laboratory processes, shorten operational cycle times, or enhance data quality/relevance. Emphasis is placed on advancements in engineering, analytical, informatics, and biological technologies and their application to cutting edge automation-assisted research. Topics include:

  • Advances and Alternatives in HT Screening Technologies
  • Advances in High Throughput Analytics and Automation
  • Agricultural Research Automation
  • Automated Chemical Synthesis
  • Chemical Biology
  • High Content and High Information Assay Methods
  • HT Profiling
  • HT Screening of Biologics
  • HT Target Identification
  • Model Organisms in Quantitative Biology
  • Phenotypic Drug Discovery
  • Physiologically Relevant Assay Systems
  • Primary and Stem Cells in High Throughput Biology
  • Sample Storage Processing
  • Tool Compound Development and Target Validation in Academia

Drug Target Biology

Drug discovery relies on a continually deeper and detailed understanding of the mechanisms underlying disease states. This track will focus on studies aimed at advancing our understanding of traditional and novel drug targets as well efforts to apply such knowledge to translational medicine. Topics include:

  • Biomarkers
  • Disease Pathways
  • Drug Repurposing
  • Epigenetics
  • Genomics
  • Metabolomics
  • Novel Drug Modalities
  • Proteomics
  • Rare Diseases
  • Systems Biology
  • Target Deconvolution
  • Target Druggability
  • Target Identification and Validation
  • Target Mechanism of Action
  • Translational Medicine

Micro- and Nanotechnologies

This track broadly encompasses new and emerging technologies including microfluidics, microarrays, microreactors, nanodevices, and nanotechnologies with emphasis on methods and materials applicable to high-throughput chemistry, biology and clinical analysis. Topics include:

  • 3D Cultures
  • Cell Patterning
  • Cellular Micro Systems
  • Droplets
  • Genomic and Proteomic Techniques
  • Micro and Nano Devices
  • Micro and Nano Fabrication
  • Micro and Nano Fluidics
  • Nanoparticles
  • Nanopores
  • Nanotoxicity
  • Nanotherapeutics
  • Optofluidics
  • Process Integration
  • Small Animal Model Manipulation

Bioanalytical Techniques

The quantitative determination of compounds in biological matricies is an important component of pharmaceutical analysis, clinical chemistry, food safety and forensics. Session topics include the latest sampling and separation technologies as well as integrated detection techniques such as mass spectrometry, molecular and functional imaging, and other label-free methods. Topics include:

  • ADME Pharmocokinetics
  • Bioimaging & Spectroscopy
  • Biomolecular Recognition (Bioassays, Biosensors)
  • Cytometry
  • Electrophoresis
  • Food-Borne Toxins Analysis
  • Forensics Analysis
  • Hyphenated Chromatography Techniques
  • Innovative Separations
  • Integration of Bioanalytical Techniques
  • Mass Spectrometry
  • Nucleic Acids (Amplification, Microarrays, Sequencing)
  • Remote and Automated Analysis
  • Renewable Bioenergy and Biomass
  • Sample Acquisition & Preparation

Informatics

Modern laboratories across all industries generate and utilize data from an ever growing number of sources with an increasing level of complexity. Accordingly, informatics plays a critical and growing role in the warehousing, visualization, and analysis of these data. This track will showcase the role of informatics in generating testable hypotheses and advancing scientific discoveries. Topics include:

  • Analysis, Computation, and Collaboration in the Cloud
  • Big Data
  • Data Interoperability
  • Data Mining
  • Emerging Informatics Technologies
  • Integrative Analysis in Research
  • Modern IT in Discovery Research
  • Multiparametric Data Analysis
  • Optimizing Scheduling and Supply Chain Logistics
  • Real-Time Data Analysis and control

Diagnostics

New diagnostic methods are making it possible to understand and detect disease states at earlier stages than before and to better predict and/or monitor the efficacy of pharmaceuticals. This track will focus on new and emerging fields such as molecular diagnostics, biomarker analysis, next-generation sequencing, point-of-care detection, and the technologies that enable these fields. Topics include:

  • Animal Health and Safety
  • Cell-based Diagnostic Systems
  • Earlier, Presymptomatic Diagnostics
  • Food and Water Safety
  • Global Health and Surveillance
  • In Vivo Approaches
  • Mass Spectrometry Based Diagnostics
  • Microfluidic Diagnostic Systems
  • Nanotechnology Enabled Systems
  • NextGen Sequencing for Diagnostics
  • Novel Molecular Diagnostic Systems
  • Novel Point-of-Care Systems
  • Rapid, Multiplexed Diagnostic Systems
  • Regulatory Strategies for New Technologies
  • Theranostics